Uppsala University : Dept. Cell and Mol. Biology : Struct. Biol. : Selmer Lab
Uppsala universitet
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Daniel Larsson

About Me

In my research I study the molecular details of life by experimental and computational means. On January 2018 I joined the Selmer Laboratory at the Department of Cell and Molecular Biology for doing structural studies of RNA and protein complexes.

Contact Details

Mailing Address
Biomedical Center
Box 596
SE-751 24 Uppsala
Visiting Address
Biomedical Center
Husargatan 3
752 37 Uppsala

My office A7:212c can be found on the 2:nd floor in corridor A7. It is most easily reached by using entrance A8 or A11 (see BMC map).

Finding at BMC: BMC page, Map of BMC
Finding to BMC (external mapping services): Google Maps, Hitta.se, Eniro.se
Office phone: +46 18 471 4601
Cell phone: +46 70 498 5470
daniel . larsson A icm . uu . se
larsson A xray . bmc . uu . se
N.B. Replace 'A' with '@' and remove spaces before use.
Uppsala University
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List of publications in peer-reviewed journals in reverse chronological order. Shared first authorship indicated with an asterisk (*).

  1. Mühlig, ... Larsson DSD, et al. (2019) Nanometre-Sized Droplets from a Gas Dynamic Virtual Nozzle. J. Appl. Cryst. 52:800-808
  2. Bielecki, ... Larsson DSD, et al. (2019) Electrospray sample injection for single-particle imaging with x-ray lasers. Sci. Adv. 5:eaav8801
  3. Pietrini, ... Larsson DSD, et al. (2018) A statistical approach to detect protein complexes at X-ray Free Electron Laser facilities. Nat. Comms. Phys. 1:92
  4. Hantke, ... Larsson DSD, et al. (2018) Rayleigh scattering microscopy for tracking and sizing nanoparticles in focused aerosol beams. IUCrJ 5:673-680
  5. Lundholm, ... Larsson DSD, et al. (2018) Considerations for three-dimensional image reconstruction from experimental data in coherent diffractive imaging. IUCrJ 5:531-541
  6. Gorkhover, ... Larsson DSD, et al. (2018) Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles. Nat. Photonics 12:150-153
  7. Okamoto K, ... Larsson DSD, et al. (2018) Cryo-EM structure of a Marseilleviridae virus particle reveals a large internal microassembly Virology 516:239-245
  8. Reddy HKN, Yoon CH, ... Larsson DSD, et al. (2017) Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac Coherent Light Source. Sci. Data 4:170079
  9. Daurer B, Okamoto K, et al. & Larsson DSD (2017) Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses. IUCrJ 4:251-262
  10. Okamoto K, Miyazaki N, Larsson DSD, et al. (2016) The infectious particle of insect-borne totivirus-like Omono River virus has raised ridges and lacks fibre complexes. Sci. Rep. 6:33170
  11. Munke A, ..., Larsson DSD, et al. (2016) Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source. Sci. Data 3:160064
  12. Schot Gvd, ..., Larsson DSD, et al. (2016) Open data set of live cyanobacterial cells imaged using an X-ray laser. Sci. Data 3:160058
  13. Hantke MF, Hasse D, ..., Larsson DSD, et al. (2016) A data set from flash X-ray imaging of carboxysomes. Sci. Data 3:160061
  14. Schot Gvd, Svenda M, ..., Larsson DSD, et al. (2015) Imaging Single Cells in a Beam of Live Cyanobacteria with an X-ray Laser. Nat. Commun. 6:5704
  15. Hantke MF, Hasse D, ..., Larsson DSD, et al. (2014) High-throughput imaging of heterogeneous cell organelles with an X-ray laser. Nature Photonics 8(12):943-949
  16. Larsson DSD, van der Spoel D (2012) Screening for the Location of RNA using the Chloride Ion Distribution in Simulations of Virus Capsids. J Chem Theory Comput 8(7):2474-2483
  17. Larsson DSD, Liljas L, van der Spoel D (2012) Virus Capsid Dissolution Studied by Microsecond Molecular Dynamics Simulations. PLoS Comput Biol 8(5):e1002502
  18. Wang F, Weckert E, Ziaja B, Larsson DSD, van der Spoel D (2011) Coherent diffraction of a single virus particle: The impact of a water layer on the available orientational information. Phys Rev E 83(3):031907
  19. Spångberg D, Larsson DSD, van der Spoel D (2011) Trajectory NG - Portable, Compressed, General Molecular Dynamics Trajectories. J Mol Model 17(10):2669-2685
  20. van der Spoel D, Marklund E, Larsson DSD, Caleman C (2011) Proteins, Lipids, and Water in the Gas Phase. Macromol Biosci 11(1):50-59
  21. Friemann R, Larsson DSD, Wang Y, van der Spoel D (2009) Molecular dynamics simulations of a membrane protein-micelle complex in vacuo. J Am Chem Soc 131(46):16606-7
  22. Marklund EG, Larsson DSD, van der Spoel D, Patriksson A, Caleman C (2009) Structural stability of electrosprayed proteins: temperature and hydration effects. Phys Chem Chem Phys 11(36):8069-78
  23. Wang* Y, Larsson* DSD, van der Spoel D (2009) Encapsulation of myoglobin in a cetyl trimethylammonium bromide micelle in vacuo: a simulation study. Biochemistry 48(5):1006-15
  24. Brindefalk B, Viklund J, Larsson D, Thollesson M, Andersson SGE (2007) Origin and evolution of the mitochondrial aminoacyl-tRNA synthetases. Mol Biol Evol 24(3):743-56

PhD thesis

On May 25, 2012 I successfully defended the thesis "Exploring the Molecular Dynamics of Proteins and Viruses" (DIVA, .pdf 68 MB).